What is a notable long-term side effect of 5-alpha-reductase inhibitors such as finasteride or dutasteride?

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Multiple Choice

What is a notable long-term side effect of 5-alpha-reductase inhibitors such as finasteride or dutasteride?

Explanation:
5-alpha-reductase inhibitors lower DHT levels by blocking the conversion of testosterone to dihydrotestosterone. DHT influences sexual function and breast tissue growth, so reducing it can lead to notable long-term effects like decreased libido, erectile dysfunction, and breast tenderness (gynecomastia). While headaches or dizziness can occur, they are not the defining long-term adverse effects, and these medications do not rapidly cure BPH; they help manage symptoms and slow progression rather than provide a cure.

5-alpha-reductase inhibitors lower DHT levels by blocking the conversion of testosterone to dihydrotestosterone. DHT influences sexual function and breast tissue growth, so reducing it can lead to notable long-term effects like decreased libido, erectile dysfunction, and breast tenderness (gynecomastia). While headaches or dizziness can occur, they are not the defining long-term adverse effects, and these medications do not rapidly cure BPH; they help manage symptoms and slow progression rather than provide a cure.

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